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Diagnostics
6.1 Laboratory diagnostics
Laboratory diagnostic procedures should not be done without prior detailed clinical-epidemiological investigations. It is important to always include the entire herd and also to bear in mind that the unborn animals play a significant role with regard to the chain of infection...
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6.2 Serum neutralisation test
The virus neutralisation test (SNT) is accepted as the „gold standard“ for BVD antibody detection. It is suitable for the detection and quantification of BVD-specific antibodies in serum...
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6.3 Antibody-ELISA
The ELISA measures antigen-antibody binding qualitatively and quantitatively. SNT only tests for neutralizing antibodies, whereas the ELISA also tests for non-neutralizing antibodies...
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6.4 Virus isolation
Virus isolation in cell culture is the gold standard of testing for BVD virus. Viral antigen is then identified immunohistochemically...
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6.5 Antigen-ELISA
The direct testing of samples via antigen-ELISA is considerably faster and cheaper than virus isolation. On the other hand, virus isolation is about ten times as sensitive as the ELISA...
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